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Diet link to Alzheimer's deepens
source: http://www.usatoday.com/news/health/2006-10-15-alzheimers-diet_x.htm?csp=34

USA TODAY
Posted 10/15/2006 11:24 PM ET
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 PASS THE FRUITS, VEGETABLES AND WHOLE GRAINS

Walter Willett of the Harvard School of Public Health and other experts recommend a Mediterranean-style diet to protect against heart disease and possibly Alzheimer's. Here's a sample menu from a new book by Willett and cookbook author Mollie Katzen.

bulletStarter: Vegetable broth with white beans
bulletEntree: Whole-wheat pasta with tomato sauce
bulletSides: Italian-style pan-sautéed broccoli, green salad with creamy balsamic dressing
bulletDessert: Fresh pineapple slices

Source: Eat, Drink, and Weigh Less: A Flexible and Delicious Way to Shrink Your Waist Without Going Hungry (Hyperion, $23.95, hardcover)

A vegetable stir-fry and a glass of red wine might go a long way toward preventing the formation of the brain gunk that can lead to Alzheimer's disease, studies report Monday.

The findings involving experiments with mice add to an increasing body of evidence, including human studies, that suggest the high-fat Western-style diet might lead not just to heart attacks but also to Alzheimer's, a disease expected to afflict up to 16 million people in the USA by 2050.

But if new research by Narayan Bhat of the Medical University of South Carolina and others pans out, Americans might be able to change that future in part by steering clear of artery-clogging foods.

Bhat took healthy lab mice and fed them a diet with lots of saturated fat and cholesterol.

After two months, he gave the mice, which were middle-aged by then, a memory test and found that those fed the bad diet flunked: They made errors finding their way around a water maze.

Mice eating the bad diet also had an increase in a toxic brain protein called beta amyloid, Bhat says. Many scientists believe that beta amyloid deposits in the brain lead to the symptoms of Alzheimer's.

Bhat presented the results on Sunday at the Society for Neuroscience annual meeting in Atlanta. The findings raise the hope that a diet low in saturated fat might prevent that build-up of beta amyloid — and Alzheimer's disease.

A study posted online this month suggests just that: The report in the Archives of Neurology found that people eating a Mediterranean-style diet — low in saturated-fat animal products and high in fruits, vegetables and whole grains — had a lower risk of Alzheimer's than people eating standard American fare.

Italians and others who live around the Mediterranean often drink red wine with dinner, and a second study at the neuroscience meeting adds to evidence suggesting that something in red wine or grapes might offer protection against Alzheimer's.

Giulio Pasinetti of the Mount Sinai School of Medicine in New York gave mice that had been genetically altered to develop Alzheimer's a small dose of red wine every day for 11 months. Then Pasinetti gave a memory test to the wine-fed mice and a control group that received no wine.

The Alzheimer's mice that were given no wine faltered on the test. But the mice that had been drinking small amounts of Cabernet Sauvignon found their way around the maze surely and swiftly, a sign that they still had a sharp memory, Pasinetti says.

Alcohol consumption can cause many health problems. So people who already drink should limit their consumption to about a single glass of red a day, Pasinetti says.

And don't expect wine or any other single food to compensate for a diet that has lots of unhealthful fat, says P. Murali Doraiswamy, an Alzheimer's expert at Duke University: "You can't wash down a double cheeseburger with a glass of red and expect to get a brain benefit."

Posted 10/15/2006 11:24 PM ET E-mail | Save | Print | Reprints & Permissions | Subscribe to stories like this





 

 

Rise in Mental Illness Linked to Unhealthy Diets, Say Studies (press release)

Posted Thursday, August 31, 2006 by NewsTarget
Printable version

Changes in diet over the past 50 years appear to be an important factor behind a significant rise in mental ill health in the UK, say two reports published today.

The Mental Health Foundation says scientific studies have clearly linked attention deficit disorder, depression, Alzheimer’s disease and schizophrenia to junk food and the absence of essential fats, vitamins and minerals in industrialised diets.

A further report, Changing Diets, Changing Minds, is also published today by Sustain, the organisation that campaigns for better food. It warns that the NHS bill for mental illness, at almost £100bn a year, will continue to rise unless the government focuses on diet and the brain in its food, farming, education and environment policies.

"Food can have an immediate and lasting effect on mental health and behaviour because of the way it affects the structure and function of the brain," Sustain’s report says. Its chairman, Tim Lang, said: "Mental health has been completely neglected by those working on food policy. If we don’t address it and change the way we farm and fish, we may lose the means to prevent much diet-related ill health."

Both reports, which have been produced collaboratively, outline the growing scientific evidence linking poor diet to problems of behaviour and mood. Rates of depression have been shown to be higher in countries with low intakes of fish, for example. Lack of folic acid, omega-3 fatty acids, selenium and the amino acid tryptophan are thought to play an important role in the illness. Deficiencies of essential fats and antioxidant vitamins are also thought to be a contributory factor in schizophrenia.

A pioneering nutrition and mental health programme, thought to be the only one of its kind in Britain, was carried out at Rotherham, South Yorkshire. According to Caroline Stokes, its research nutritionist, the mental health patients she saw generally had the poorest diets she had ever come across. "They are eating lots of convenience foods, snacks, takeaways, chocolate bars, crisps. It’s very common for clients to be drinking a litre or two of cola a day. They get lots of sugar but a lot of them are eating only one portion of fruit or vegetable a day, if that."

The therapy includes omega-3 fatty acids and multivitamins, with advice on cutting out junk food and replacing it with oily fish, leafy vegetables for folic acid, Brazil nuts for selenium, and food providing tryptophan.

Some patients who resist treatment with drugs accept nutritional therapy and most have reported an improvement in mood and energy. Ms Stokes said: "Within the first month there’s been a significant reduction in depression. We’ve had letters from [the patients’] psychiatrists saying they can see a huge difference."

One sufferer who benefited from a dietary change was James McLean, who was at university when first diagnosed with bipolar disorder (manic depression). After he had been sectioned repeatedly, his father read about the role of nutrition in mental health. The pair went privately to the Brain Bio Centre, in London, where Mr McLean’s nutrient levels were checked; he was allergic to gluten and yeast and was given supplements, including vitamin B and essential fatty acids.

"I’d been eating lots of intense carbohydrate foods ... because they were cheap, and very little fruit or vegetables," Mr McLean said. Now, he excludes wheat from his diet too. He added: "I have more energy and confidence, I sleep better, and I came off the anti-psychotic drugs, although I still take mood stabilising ones."

Andrew McCulloch, chief executive of the Mental Health Foundation, acknowledged that mental illness results from a complex interplay of biological, social, psychological and environmental factors, but thought diet should be an everyday component of mental health care. "It costs £1,000 a week to keep someone in a psychiatric hospital. How much does good food cost? We need mentally healthy school meals, and mentally healthy hospital foods," he said.

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Junk food can lead to mental illness

junk foodAccording to reports published last week by the Mental Health Foundation and Sustain, an organization that campaigns for better food in the UK, junk food and the absence of essential fats, vitamins and minerals appear to have contributed to increasing mental illness: attention deficit disorder (ADD), depression, Alzheimer's disease and schizophrenia.

Nutritionist Caroline Stokes said that mental health patients had the poorest diets, "eating lots of convenience foods, snacks, takeaways, chocolate bars, crisps." Additionally, they are "drinking a litre or two of cola a day."

source: http://www.slashfood.com/2006/09/02/junk-food-can-lead-to-mental-illness/

 

 

How much will that diet cost you? (9/03/2006)